abstract：:Finding the neuroanatomical correlates of prematurity is vital to understanding which structures are affected, and to designing efficient prevention and treatment strategies. Converging results reveal that thalamic abnormalities are important indicators of prematurity. However, little is known about the localization o...

journal_title：Brain structure & function

authors： Lao Y,Wang Y,Shi J,Ceschin R,Nelson MD,Panigrahy A,Leporé N

更新日期：2016-01-01 00:00:00

abstract：:The ventral striatum (VS) is of particular interest in the study of neuropsychiatric disorders. In this study, performed on non-human primates, we associated local perturbation with monosynaptic axonal tracer injection into medial, central and lateral VS to characterize anatomo-functional circuits underlying the respe...

journal_title：Brain structure & function

authors： Sgambato-Faure V,Worbe Y,Epinat J,Féger J,Tremblay L

更新日期：2016-01-01 00:00:00

abstract：:Rapid behavioral responses to unexpected events in the acoustic environment are critical for survival. Stimulus-specific adaptation (SSA) is the process whereby some auditory neurons respond better to rare stimuli than to repetitive stimuli. Most experiments on SSA have been performed under anesthesia, and it is unkno...

journal_title：Brain structure & function

authors： Duque D,Malmierca MS

更新日期：2015-11-01 00:00:00

abstract：:The present study documents the morphology of neurons in several regions of the neocortex from the bottlenose dolphin (Tursiops truncatus), the North Atlantic minke whale (Balaenoptera acutorostrata), and the humpback whale (Megaptera novaeangliae). Golgi-stained neurons (n = 210) were analyzed in the frontal and temp...

journal_title：Brain structure & function

authors： Butti C,Janeway CM,Townshend C,Wicinski BA,Reidenberg JS,Ridgway SH,Sherwood CC,Hof PR,Jacobs B

更新日期：2015-11-01 00:00:00

abstract：:In the primate cerebral cortex, dendritic spines rapidly increase in number after birth up to infancy or mid-childhood, and then decrease towards adulthood. Abnormalities in these processes accompany several psychiatric disorders. In this study, we examined developmental changes of basal dendrites and spines of layer ...

journal_title：Brain structure & function

authors： Sasaki T,Aoi H,Oga T,Fujita I,Ichinohe N

更新日期：2015-11-01 00:00:00

abstract：:Although several novel approaches for hippocampal subregion delineation have been developed, they need to be applied prospectively and may be limited by long scan times, the use of high field (>3T) imaging systems, and limited reliability metrics. Moreover, the majority of MR imaging data collected to date has employe...

journal_title：Brain structure & function

authors： Rhindress K,Ikuta T,Wellington R,Malhotra AK,Szeszko PR

更新日期：2015-11-01 00:00:00

abstract：:The process of learning mainly depends on the ability to store new information, while the ability to retrieve this information and express appropriate behaviors are also crucial for the adaptation of individuals to environmental cues. Thereby, all three components contribute to the cognitive fitness of an individual. ...

journal_title：Brain structure & function

authors： Zhang CL,Houbaert X,Lepleux M,Deshors M,Normand E,Gambino F,Herzog E,Humeau Y

更新日期：2015-11-01 00:00:00

abstract：:Neocortical layer VI is critically involved in thalamocortical activity changes during the sleep/wake cycle. It receives dense projections from thalamic nuclei sensitive to the wake-promoting neuropeptides orexins, and its deepest part, layer VIb, is the only cortical lamina reactive to orexins. This convergence of wa...

journal_title：Brain structure & function

authors： Hay YA,Andjelic S,Badr S,Lambolez B

更新日期：2015-11-01 00:00:00

abstract：:The frontal pole corresponds to Brodmann area (BA) 10, the largest single architectonic area in the human frontal lobe. Generally, BA10 is thought to contain two or three subregions that subserve broad functions such as multitasking, social cognition, attention, and episodic memory. However, there is a substantial deb...

journal_title：Brain structure & function

authors： Moayedi M,Salomons TV,Dunlop KA,Downar J,Davis KD

更新日期：2015-09-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) are Zn(2+)-dependent endopeptidases considered to be essential for normal brain development and neuroplasticity by modulating extracellular matrix proteins, receptors, adhesion molecules, growth factors and cytoskeletal proteins. Specifically, MMP-3 has recently been implicated in syna...

journal_title：Brain structure & function

authors： Aerts J,Nys J,Moons L,Hu TT,Arckens L

更新日期：2015-09-01 00:00:00

abstract：:The mammalian superior paraolivary nucleus (SPON) is a major source of GABAergic inhibition to neurons in the inferior colliculus (IC), a well-studied midbrain nucleus that is the site of convergence and integration for the majority ascending auditory pathways en route to the cortex. Neurons in the SPON and IC exhibit...

journal_title：Brain structure & function

authors： Felix RA 2nd,Magnusson AK,Berrebi AS

更新日期：2015-09-01 00:00:00

abstract：:Although type 1 cannabinoid receptors (CB1Rs) are expressed abundantly throughout the brain, the presence of type 2 cannabinoid receptors (CB2Rs) in neurons is still somewhat controversial. Taking advantage of newly designed CB1R and CB2R mRNA riboprobes, we demonstrate by PCR and in situ hybridization that transcript...

journal_title：Brain structure & function

authors： Sierra S,Luquin N,Rico AJ,Gómez-Bautista V,Roda E,Dopeso-Reyes IG,Vázquez A,Martínez-Pinilla E,Labandeira-García JL,Franco R,Lanciego JL

更新日期：2015-09-01 00:00:00

abstract：:Previous diffusion tensor imaging (DTI) studies have shown that various factors can affect white matter (WM) tract diffusivity. The aim of the present study was to investigate the effects of childhood adversity (CA), age and gender on WM diffusivity in tracts that are thought to be involved in emotional regulation in ...

journal_title：Brain structure & function

authors： Ugwu ID,Amico F,Carballedo A,Fagan AJ,Frodl T

更新日期：2015-07-01 00:00:00

abstract：:It is well established that environmental influences play a key role in sculpting neuronal connectivity in the brain. One example is the olfactory sensory map of topographic axonal connectivity. While intrinsic odorant receptor signaling in olfactory sensory neurons (OSN) determines anterior-posterior counter gradient...

journal_title：Brain structure & function

authors： Login H,Butowt R,Bohm S

更新日期：2015-07-01 00:00:00

abstract：:Coordinated modulation of sympathetic and parasympathetic nervous activity is required for physiological regulation of tissue function. Anatomically, whilst the peripheral sympathetic and parasympathetic pathways are separate, the distribution of premotor neurons in higher brain regions often overlaps. This co-distrib...

journal_title：Brain structure & function

authors： Hettigoda NS,Fong AY,Badoer E,McKinley MJ,Oldfield BJ,Allen AM

更新日期：2015-07-01 00:00:00

abstract：:Emerging data support roles for microRNA (miRNA) in the pathogenesis of various neurologic disorders including epilepsy. MicroRNA-134 (miR-134) is enriched in dendrites of hippocampal neurons, where it negatively regulates spine volume. Recent work identified upregulation of miR-134 in experimental and human epilepsy....

journal_title：Brain structure & function

authors： Jimenez-Mateos EM,Engel T,Merino-Serrais P,Fernaud-Espinosa I,Rodriguez-Alvarez N,Reynolds J,Reschke CR,Conroy RM,McKiernan RC,deFelipe J,Henshall DC

更新日期：2015-07-01 00:00:00

abstract：:The adult dentate gyrus produces new neurons that morphologically and functionally integrate into the hippocampal network. In the adult brain, most excitatory synapses are ensheathed by astrocytic perisynaptic processes that regulate synaptic structure and function. However, these processes are formed during embryonic...

journal_title：Brain structure & function

authors： Krzisch M,Temprana SG,Mongiat LA,Armida J,Schmutz V,Virtanen MA,Kocher-Braissant J,Kraftsik R,Vutskits L,Conzelmann KK,Bergami M,Gage FH,Schinder AF,Toni N

更新日期：2015-07-01 00:00:00

abstract：:The 30-amino acid peptide Y-P30, generated from the N-terminus of the human dermcidin precursor protein, has been found to promote neuronal survival, cell migration and neurite outgrowth by enhancing the interaction of pleiotrophin and syndecan-3. We now show that Y-P30 activates Src kinase and extracellular signal-re...

journal_title：Brain structure & function

authors： Neumann JR,Dash-Wagh S,Jüngling K,Tsai T,Meschkat M,Räk A,Schönfelder S,Riedel C,Hamad MI,Wiese S,Pape HC,Gottmann K,Kreutz MR,Wahle P

更新日期：2015-07-01 00:00:00

abstract：:Three populations of neurons expressing the vesicular glutamate transporter 2 (Vglut2) were recently described in the A10 area of the mouse midbrain, of which two populations were shown to express the gene encoding, the rate-limiting enzyme for catecholamine synthesis, tyrosine hydroxylase (TH).One of these population...

journal_title：Brain structure & function

authors： Nordenankar K,Smith-Anttila CJ,Schweizer N,Viereckel T,Birgner C,Mejia-Toiber J,Morales M,Leao RN,Wallén-Mackenzie Å

更新日期：2015-07-01 00:00:00

abstract：:Previous work in the precocious rodent Octodon degus has shown that exposure to early life stress (ELS) (induced by repeated parental separation) results in changes of excitatory, inhibitory and modulatory transmitter systems in prefrontal and limbic regions of the male brain. The aim of this study was to test the hyp...

journal_title：Brain structure & function

authors： Kunzler J,Braun K,Bock J

更新日期：2015-03-01 00:00:00

abstract：:Stress impacts differently in distinct brain regions. However, so far few studies have focused on the differential responses triggered by stressful stimuli on the intrinsic functional heterogeneity of the hippocampal axis. In this study, we assessed the functional and structural alterations caused by exposure to a chr...

journal_title：Brain structure & function

authors： Pinto V,Costa JC,Morgado P,Mota C,Miranda A,Bravo FV,Oliveira TG,Cerqueira JJ,Sousa N

更新日期：2015-03-01 00:00:00

abstract：:Early-life sleep deprivation (ESD) is a serious condition with severe metabolic sequelae. The pineal hormone melatonin plays an important role in homeostatic regulation of metabolic function. Considering norepinephrine-mediated Ca(2+) influx and subsequent protein kinase A (PKA) activation is responsible for downstrea...

journal_title：Brain structure & function

authors： Chen LY,Tiong C,Tsai CH,Liao WC,Yang SF,Youn SC,Mai FD,Chang HM

更新日期：2015-03-01 00:00:00

abstract：:Similar to memory formation, memory extinction is also a new learning process that requires synaptic plasticity. Actin rearrangement is fundamental for synaptic plasticity, however, whether actin rearrangement in the infralimbic cortex (IL) plays a role in memory extinction, as well as the mechanisms underlying it, re...

journal_title：Brain structure & function

authors： Bi AL,Wang Y,Zhang S,Li BQ,Sun ZP,Bi HS,Chen ZY

更新日期：2015-03-01 00:00:00

abstract：:The effect of intracortical microstimulation has been studied in several cortical areas from motor to sensory areas. The frontal pole has received particular attention, and several microstimulation studies have been conducted in the frontal eye field, supplementary eye field, and the premotor ear-eye field, but no mic...

journal_title：Brain structure & function

authors： Lanzilotto M,Perciavalle V,Lucchetti C

更新日期：2015-03-01 00:00:00

abstract：:Multisensory integration does not only recruit higher-level association cortex, but also low-level and even primary sensory cortices. Here, we will describe and quantify two types of anatomical pathways, a thalamocortical and a corticocortical that possibly underlie short-latency multisensory integration processes in ...

journal_title：Brain structure & function

authors： Henschke JU,Noesselt T,Scheich H,Budinger E

更新日期：2015-03-01 00:00:00

abstract：:The extensive and increasing use of structural neuroimaging in the neurosciences rests on the assumption of an intimate relationship between structure and function in the human brain. However, few studies have examined the relationship between advanced magnetic resonance imaging (MRI) indices of cerebral structure and...

journal_title：Brain structure & function

authors： Elvsåshagen T,Moberget T,Bøen E,Hol PK,Malt UF,Andersson S,Westlye LT

更新日期：2015-03-01 00:00:00

abstract：:The default mode network (DMN) in humans has been extensively studied using seed-based correlation analysis (SCA) and independent component analysis (ICA). While DMN has been observed in monkeys as well, there are conflicting reports on whether they exist in rodents. Dogs are higher mammals than rodents, but cognitive...

journal_title：Brain structure & function

authors： Kyathanahally SP,Jia H,Pustovyy OM,Waggoner P,Beyers R,Schumacher J,Barrett J,Morrison EE,Salibi N,Denney TS,Vodyanoy VJ,Deshpande G

更新日期：2015-03-01 00:00:00

abstract：:Recently, there have been great interests for computer-aided diagnosis of Alzheimer's disease (AD) and its prodromal stage, mild cognitive impairment (MCI). Unlike the previous methods that considered simple low-level features such as gray matter tissue volumes from MRI, and mean signal intensities from PET, in this p...

journal_title：Brain structure & function

authors： Suk HI,Lee SW,Shen D,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2015-03-01 00:00:00

abstract：:Diffusion tensor imaging (DTI) has become a valuable tool to investigate white matter integrity in the brain. DTI also gives contrast in gray matter, which has been relatively little explored in studies assessing post-injury structural abnormalities. The present study was designed to compare white and gray matter reor...

journal_title：Brain structure & function

authors： Sierra A,Laitinen T,Gröhn O,Pitkänen A

更新日期：2015-03-01 00:00:00

abstract：:Using T 1-weighted MRI at two different magnetic field strengths, the enhanced longitudinal relaxivity due to paramagnetic manganese ions in mouse brain in vivo is shown to reflect reduced intracellular mobility. One day after systemic administration of manganese chloride, increases of the longitudinal relaxation rate...

journal_title：Brain structure & function

authors： Watanabe T,Frahm J,Michaelis T

更新日期：2015-01-01 00:00:00

abstract：:Chaining or cascading of different actions and responses is necessary to accomplish a goal. Yet, little is known about the functional neuroanatomical-electrophysiological mechanisms mediating these processes. Computational models suggest that medium spiny neurons (MSNs) play an important role in action cascading, but ...

journal_title：Brain structure & function

authors： Beste C,Saft C

更新日期：2015-01-01 00:00:00

abstract：:Neuroligins are transmembrane cell adhesion proteins with a key role in the regulation of excitatory and inhibitory synapses. Based on previous in vitro and ex vivo studies, neuroligin-1 (NL1) has been suggested to play a selective role in the function of glutamatergic synapses. However, the role of NL1 has not yet be...

journal_title：Brain structure & function

authors： Jedlicka P,Vnencak M,Krueger DD,Jungenitz T,Brose N,Schwarzacher SW

更新日期：2015-01-01 00:00:00

abstract：:The organization of the serotonergic system, one of the most important neurotransmitter systems in the brain, has been carefully analyzed in most vertebrate groups, and major shared characteristics have been described, although traits particular to each vertebrate class have also been found. The present study is the f...

journal_title：Brain structure & function

authors： López JM,González A

更新日期：2015-01-01 00:00:00

abstract：:The Ly-6 superfamily of proteins, which affects diverse processes in the immune system, has attracted renewed attention due to the ability of some Ly-6 proteins to bind to and modulate the function of neuronal nicotinic acetylcholine receptors (nAChRs). However, there is a scarcity of knowledge regarding the distribut...

journal_title：Brain structure & function

authors： Thomsen MS,Cinar B,Jensen MM,Lyukmanova EN,Shulepko MA,Tsetlin V,Klein AB,Mikkelsen JD

更新日期：2014-11-01 00:00:00

abstract：:Selective attention to features of interest facilitates object processing in a cluttered and dynamic environment. Previous research found that distinct networks of regions across cortex are activated depending on the attended feature. These networks typically consist of posterior feature-preferring regions and anterio...

journal_title：Brain structure & function

authors： Mayer KM,Vuong QC

更新日期：2014-11-01 00:00:00

abstract：:Diffusion-weighted magnetic resonance spectroscopy of brain metabolites offers unique access to compartment-specific microstructural information on neural tissue. Here, we investigated in detail the diffusion characteristics of the neuronal/axonal markers N-acetylaspartate + N-acetyl aspartyl glutamate (tNAA) in a sma...

journal_title：Brain structure & function

authors： Ronen I,Budde M,Ercan E,Annese J,Techawiboonwong A,Webb A

更新日期：2014-09-01 00:00:00

abstract：:Exposure to stress activates the hypothalamic-pituitary-adrenal (HPA) axis that stimulates glucocorticoid (GC) release from the adrenal. These hormones exert numerous effects in the body and brain and bind to a.o. glucocorticoid receptors (GR) expressed in the limbic system, including the hippocampus and amygdala. Hyp...

journal_title：Brain structure & function

authors： Wang Q,Verweij EW,Krugers HJ,Joels M,Swaab DF,Lucassen PJ

更新日期：2014-09-01 00:00:00

abstract：:Inputs to apical dendritic tufts have been considered to be crucial for associative learning, attention and similar ''feedback'' interactions and are located in neocortical layer Ia. Excitatory thalamic projections to apical tufts in layer Ia have been well characterized and their role in the cortical circuit has been...

journal_title：Brain structure & function

authors： Ramos-Moreno T,Clascá F

更新日期：2014-09-01 00:00:00

abstract：:The variety of different causal theories together with inconsistencies about the anatomical brain markers emphasize the heterogeneity of developmental dyslexia. Attempts were made to test on a behavioral level the existence of subtypes of dyslexia showing distinguishable cognitive deficits. Importantly, no research wa...

journal_title：Brain structure & function

authors： Jednoróg K,Gawron N,Marchewka A,Heim S,Grabowska A

更新日期：2014-09-01 00:00:00

abstract：:Glucose metabolism produces, by oxidative phosphorylation, more than 15 times the amount of energy generated by aerobic glycolysis. Nonetheless, aerobic glycolysis remains a prevalent metabolic pathway in the brain. Here we review evidence suggesting that this pathway contributes essential molecules to the biomass of ...

journal_title：Brain structure & function

authors： Bauernfeind AL,Barks SK,Duka T,Grossman LI,Hof PR,Sherwood CC

更新日期：2014-07-01 00:00:00